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Medical science is constantly evolving. Through the years, it continues to look for solutions and treatments for various medical diseases. One of the remarkable discoveries that science stumbled into is the liposome. This is a recent breakthrough that is believed to be potent in treating many medical malfunctions. It is also used to help administer drugs more efficiently and increase the success rate of organ transplant among other functions.
Liposomes are microscopic vesicles that are developed in a laboratory. These are made from phospholipids that may be produced naturally or extracted from other sources. The outer wall of the liposome is composed of lipids that are similar to the composition of cell walls. Hence, the liposomes can directly interact with the cells. These tiny, spheroid bubbles typically have a watery core.
This structure is most commonly used in introducing medicines to the patient's body. Using this as a drug vessel has proven to be more effective than any other methods of administering the medications. The vesicles are uniquely designed to deliver the drugs to a particular part of the human body through the diffusion process. This makes it a perfect choice for administering antibodies to directed parts of the body. This can also carry hydrophobic drugs because of its double-layered membrane.
Moreover, this can extend the delivery time of the administered drugs. The bi-layered sphere slowly releases the drugs in interval over a period of time. This is hypothetically believed to help reduce side-effects since the direct impact of the applied medications are limited only to the affected tissues. This also means that the efficiency of the drugs is maximized.
The vesicles are also believed to be an effective cancer fighting agent. The spheroids can mark the cancer cells. It can also slip right to the tumor by going through the blood flow. This stays in the bloodstreams as well because of its miniature size and its property that is similar to the blood vessels. The drug vessels cannot pass through the endothelial wall as opposed to cancer cells, which are naturally leaky.
The vesicles can help neutralize autoimmune reactions of the body. Rejections occur in many transplant surgeries when the body identifies the transplanted organ as foreign. The immune system's natural reaction would be to attack the entity in order to protect the body from infestation. The use of artificial lipid can suppress the progress of immune system, so the body has enough time to accommodate the newly introduced organ.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
The vesicles can be produced in varying sizes. Typically, these are developed small enough so the white blood cells can easily engulf it before releasing the drug it carries. Decision has to be made before production to know the size and number of vesicles to be produced. If there is a need, reproduction must also be considered.
The only possible disadvantage with liposome is the cost of producing it. Mass production is not currently feasible because the vessels do not last long following its creation. Stability may also be an issue. On occasion, the drugs may be mixed unintentionally. Other than that, this is a promising breakthrough.
Liposomes are microscopic vesicles that are developed in a laboratory. These are made from phospholipids that may be produced naturally or extracted from other sources. The outer wall of the liposome is composed of lipids that are similar to the composition of cell walls. Hence, the liposomes can directly interact with the cells. These tiny, spheroid bubbles typically have a watery core.
This structure is most commonly used in introducing medicines to the patient's body. Using this as a drug vessel has proven to be more effective than any other methods of administering the medications. The vesicles are uniquely designed to deliver the drugs to a particular part of the human body through the diffusion process. This makes it a perfect choice for administering antibodies to directed parts of the body. This can also carry hydrophobic drugs because of its double-layered membrane.
Moreover, this can extend the delivery time of the administered drugs. The bi-layered sphere slowly releases the drugs in interval over a period of time. This is hypothetically believed to help reduce side-effects since the direct impact of the applied medications are limited only to the affected tissues. This also means that the efficiency of the drugs is maximized.
The vesicles are also believed to be an effective cancer fighting agent. The spheroids can mark the cancer cells. It can also slip right to the tumor by going through the blood flow. This stays in the bloodstreams as well because of its miniature size and its property that is similar to the blood vessels. The drug vessels cannot pass through the endothelial wall as opposed to cancer cells, which are naturally leaky.
The vesicles can help neutralize autoimmune reactions of the body. Rejections occur in many transplant surgeries when the body identifies the transplanted organ as foreign. The immune system's natural reaction would be to attack the entity in order to protect the body from infestation. The use of artificial lipid can suppress the progress of immune system, so the body has enough time to accommodate the newly introduced organ.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
The vesicles can be produced in varying sizes. Typically, these are developed small enough so the white blood cells can easily engulf it before releasing the drug it carries. Decision has to be made before production to know the size and number of vesicles to be produced. If there is a need, reproduction must also be considered.
The only possible disadvantage with liposome is the cost of producing it. Mass production is not currently feasible because the vessels do not last long following its creation. Stability may also be an issue. On occasion, the drugs may be mixed unintentionally. Other than that, this is a promising breakthrough.
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